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Case Study: Head and Neck Cancer Clinical Trials Patient Recruitment

Nanobiotix

A phase 3 clinical trial evaluating a first-in-class radioenhancer for locally advanced head and neck cancer.

Nanobiotix

THE CLINICAL TRIAL
Head and neck cancer represents approximately 4% of all cancer cases in the United States, and initial stages of the disease are typically managed through surgery or radiotherapy alone. This clinical trial was examining the effectiveness, performance, and safety of an investigational radioenhancer used in conjunction with radiation therapy and cetuximab, compared to radiation therapy with cetuximab alone. The clinical trial focused on treatment-naïve, elderly participants with locally advanced, platinum-ineligible head and neck squamous cell carcinoma (LA-HNSCC).

 

THE PROJECT
For over 17 years, Nanobiotix has been at the forefront of nanomedicine, introducing an innovative approach to medicine. Unlike traditional methods rooted in biology or chemistry, their therapeutic technologies leverage physical principles at the nanoscale. Their investigational radioenhancer is being developed for various solid tumor indications and therapeutic combinations. To create a compelling study brand that informs and captivates patients about this promising treatment option, Nanobiotix enlisted the patient recruitment expertise of Stark / Raving. This collaboration aimed to establish a robust study brand that spans their entire clinical trial portfolio, engaging patients and providing them with valuable education on this potential treatment option.

KEY OUTCOMES

  • Saved 4% of their total SaaS spend in the first 3 months, and 16% in the first year working with Zylo
  • Revealed 30% overspend in budget
  • Saved 10 hours per week, allowing more focus on strategic work
  • 75 contracts negotiated by Zylo in year one
  • Reduced number of applications by 10% while experiencing rapid growth
Patient recruitment clinical study branding development poster
Patient recruitment clinical study branding development poster
Patient recruitment clinical study branding and content development

Developing a study brand for a potential groundbreaking treatment

Nanobiotix aims to enhance the effectiveness of radiation therapy while minimizing the impact on surrounding healthy tissues, with their investigational radioenhancer called NBTXR3. Their ultimate goal is to establish this new approach as a new standard of care in cancer treatment. To swiftly raise awareness about the study and educate site staff on this innovative approach, the Stark / Raving team devised a strategic plan that introduced Nanobiotix to the clinical team. This approach included patient- and site-facing materials that effectively educated both audiences about the potential benefits of the combined treatment approach for head and neck cancer.

Patient recruitment clinical study branding and content development
Patient recruitment clinical study branding development brochure
Patient recruitment clinical study branding and content development
Patient recruitment clinical study branding development brochure

Making a complex study design approachable for study participants and site staff

Navigating head and neck cancer poses significant challenges for both patients and their families. When clinical trials enter the picture, with their array of tests, procedures, and treatment plans, it can further complicate matters. Our objective was to simplify the study details and intricate design in a visually accessible manner, empowering patients throughout their participation. Additionally, we created a set of study tools specifically tailored for healthcare professionals involved in the trial. These resources served to keep the clinical trial at the forefront of their minds and supported the seamless implementation of the protocol.

Patient recruitment clinical study branding and content development
Patient recruitment clinical study branding and content development
Patient recruitment clinical study branding and content development

Learn how we can put our patient recruitment solutions to work for your next clinical trial.

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